Page 306 - Vitamin D and Cancer

12 The Vitamin D Signaling Pathway in Mammary Gland and Breast Cancer 293

57. Mehta RG, Moriarty RM, Mehta RR et al (1997) Prevention of preneoplastic mammary lesion
development by a novel vitamin D analogue, 1alpha-hydroxyvitamin D5. J Natl Cancer Inst
89:212–218
58. Anzano M, Smith J, Uskokovic M et al (1994) 1a-Dihydroxy-16-ene-23-yne-26, 27-hexaflu-
orocholcalciferol (Ro24–5531), a new deltanoid (vitamin D analog) for prevention of breast
cancer of breast cancer in the rat. Cancer Res 54:1653–1656
59. Mehta R, Hawthorne M, Uselding L et al (2000) Prevention of N-methyl-N-nitrosourea-
induced mammary carcinogenesis in rats by 1a-hydroxyvitamin D5. J Natl Cancer Inst
92:1836–1840
60. Zinser GM, Suckow M, Welsh JE (2005) Vitamin D receptor (VDR) ablation alters carcino-
gen-induced tumorigenesis in mammary gland, epidermis and lymphoid tissues. J Steroid
Biochem Mol Biol 97:153–164
61. Zinser GM, Welsh JE (2004) Vitamin D receptor status alters mammary gland morphology
and tumorigenesis in MMTV-neu mice. Carcinogenesis 25:2361–2372
62. Zinser GM, Sundberg JP, Welsh JE (2002) Vitamin D(3) receptor ablation sensitizes skin to
chemically induced tumorigenesis. Carcinogenesis 23:103–109
63. Agadir A, Lazzaro G, Zheng Y et al (1999) Resistance of HBL100 human breast epithelial
cells to vitamin D action. Carcinogenesis 20:577–582
64. Solomon C, Kremer R, White JH et al (2001) Vitamin D resistance in RAS-transformed kera-
tinocytes: mechanism and reversal strategies. Radiat Res 155:156–162
65. Albertson DG, Ylstra B, Segraves R et al (2000) Quantitative mapping of amplicon structure
by array CGH identifies CYP24 as a candidate oncogene. Nat Genet 25:144–146
66. Abedin SA, Banwell CM, Colston KW et al (2006) Epigenetic corruption of VDR signalling
in malignancy. Anticancer Res 26:2557–2566
67. Banwell CM, MacCartney DP, Guy M et al (2006) Altered nuclear receptor corepressor expression
attenuates vitamin D receptor signaling in breast cancer cells. Clin Cancer Res 12:2004–2013
68. Malinen M, Saramäki A, Ropponen A et al (2008) Distinct HDACs regulate the transcrip-
tional response of human cyclin-dependent kinase inhibitor genes to Trichostatin A and
1alpha, 25-dihydroxyvitamin D3. Nucleic Acids Res 36:121–132
69. Hansen CM, Rohde L, Madsen MW et al (2001) MCF-7/VD(R): a new vitamin D resistant
cell line. J Cell Biochem 82:422–436
70. Narvaez CJ, Vanweelden K, Byrne I et al (1996) Characterization of a vitamin D3-resistant
MCF-7 cell line. Endocrinol 137:400–409
71. Narvaez CJ, Byrne BM, Romu S et al (2003) Induction of apoptosis by 1, 25-dihydroxyvita-
min D(3) in MCF-7 Vitamin D(3)-resistant variant can be sensitized by TPA. J Steroid
Biochem Mol Biol 84:199–209
72. Kemmis CM, Welsh JE (2008) Mammary epithelial cell transformation is associated with
deregulation of the vitamin D pathway. J Cell Biochem Sept 2 [Epub ahead of print]
73. Elenbaas B, Spirio L, Koerner F et al (2001) Human breast cancer cells generated by onco-
genic transformation of primary mammary epithelial cells. Genes Dev 15:50–65
74. Mittal MK, Myers JN, Misra S et al (2008) In vivo binding to and functional repression of the
VDR gene promoter by SLUG in human breast cells. Biochem Biophys Res Commun
372:30–34
75. Pálmer HG, Larriba MJ, García JM et al (2004) The transcription factor SNAIL represses vita-
min D receptor expression and responsiveness in human colon cancer. Nat Med 10:917–919
76. Binkley N, Novotny R, Krueger D et al (2007) Low vitamin D status despite abundant sun
exposure. J Clin Endocrinol Metab 92:2130–2135
77. Kommagani R, Payal V, Kadakia MP. Differential regulation of vitamin D receptor (VDR) by
the p53 Family: p73-dependent induction of VDR upon DNA damage. J Biol Chem. 2007 Oct
12:282(41);29847–54. Epub 2007 Aug 23