Page 243 - Vitamin D and Cancer

230 C.M. Barnett and T.M. Beer

Decreased risk of prostate cancer in men older than 57yo with higher levels of 1,25-OH 2 , especially in those men with low 25-OH levels High 1,25-OH 2 associated with non-significant reduction in prostate cancer risk Low levels of 25-OH are associated with increased risk of earlier and more aggressive prostate cancer

Conclusions Null Null Null Null Null

% Vitamin D deficient ~50% ~10% ~20% None >60% ~50% ~20% 20% 19% ~50% <15%

Number of subjects Case-control studies of vitamin D level and prostate cancer risk 181 cases, 181 controls 61 cases, 122 controls 232 cases, 414 controls 136 cases, 136 controls 149 cases, 566 controls 622 cases, 1451 controls 460 cases, 460 controls 83 cases, 166 controls 492 cases, 644 controls 296 cases, 297 con

Population African-American and Caucasian men in CA Caucasians in MD US physicians Japanese Americans in HI Finnish men Scandanavian men US health professionals Eastern US Caucasians US Physicians Finnish men Caucasian Americans

Table 10.4 Study Corder (1993) [90] Braun (1995) [94] Gann (1996) [96] Nomura (1998) [99] Ahohen (2000) [89] Tuohimaa (2004) [92] Platz (2004) [98] Jacobs (2004) [97] Li et al. (2007) [91] Faupel-Badger et al. (2007) [95] Ahn et al. (2008) [93]