Page 352 - Vitamin D and Cancer

Index

A Calcium-sensing surface receptor (CaR),
Activating protein 1 (AP-1), 28, 148, 153, 14, 153, 200, 205
156–158, 163, 254, 259 Cancer prevention, 15, 18, 63, 64, 86,
Acute myeloid leukemia (AML), 155, 156, 180, 186–187, 208, 209, 280,
158, 162, 163, 256–258, 263, 264, 267 285–287, 289, 295, 301, 302, 305–308,
Acute promyelocytic leukemia (APL), 35, 315–323
145, 260, 263 Cardiovascular (CV), 59, 89, 106, 107,
Adenomatous polyposis coli (APC), 56, 147, 115–132, 187, 333
177, 306 CCAAT/enhancer binding protein (C/EBP),
1a,25dihydroxyvitaminD3 (1a,25(OH) D ), 2, 31, 151, 157, 162–163, 259, 260
3
2
26, 27, 29, 32–41, 43 Cdk5. See Cyclin-dependent kinase 5
AKT. See Serine/threonine-specific protein Chemoprevention, 36, 54, 59, 63, 64, 145,
kinase B 146, 175–187, 207, 209
Alkaline phosphatase (Alk Pase), 146, 154 Chemoprevention and treatment, 186
All-trans retinoic acid (ATRA), Chemotherapy, 59, 103, 145, 232, 237–240,
105, 145, 263 262–264, 280, 284, 285, 307
AML. See Acute myeloid leukemia Cholecalciferol (D ), 76, 90, 178,
3
Androgen (A), 9, 151, 152, 159, 179, 180 184–185, 195–196, 257, 297, 299, 300,
Androgen receptor (AR), 9, 29, 31, 148, 151, 306, 308, 309
152, 316 CI. See Confidence interval
Angiogenesis, 54, 55, 57, 58, 74, 99–107, 232, 9 cis retinoic acid (9 cRA), 105, 183, 263
258, 304, 316 Co-activator (CoA), 27, 29, 30, 39, 147, 148,
Anti-inflammatory actions, 14, 54–64 154, 196–198, 206, 224, 260, 268
Colorectal cancer (CRC), 4, 5, 7, 10,
13–15, 55, 56, 63, 75, 78–81, 89, 91,
B 106, 147, 176–178, 180, 185, 186,
Bacis helix loop helix (bHLH), 31 295–309, 315
Bone morphogenetic protein (BMP), 151 Combination therapy, 16, 17, 59, 60,
Breast cancer (BC), 8–9, 37–41, 55, 268, 280
74, 83–87, 89, 91, 102, 145, 149–150, Confidence interval (CI), 78–81, 83–91, 121,
176, 180–182, 185, 193, 194, 232, 125–128, 185, 186, 238, 239, 296,
279–290, 316 300–304, 306, 308
C-reactive protein (CRP),
130, 131
C CV. See Cardiovascular
Calcitriol, 53–64, 107, 125, 131, 187, 196, Cyclin-dependent kinase 5 (Cdk5), 157,
233–240, 257, 297, 299, 316, 329 160–163
Calcium (Ca), 4, 59, 90, 91, 147, 163, 177, “Cyclin-like” neuronal Cdk5 activator
180, 181, 199–201, 210, 230, 258, 268 (Nck5a), 157, 160

D.L. Trump and C.S. Johnson (eds.), Vitamin D and Cancer, 339
DOI 10.1007/978-1-4419-7188-3, © Springer Science+Business Media, LLC 2011