Page 355 - Vitamin D and Cancer

342 Index

Retinoic acid receptor (RAR), 29, 35, TRIP2/DRIP205. See Thyroid hormone
148, 260 receptor interactor 2
Retinoid X receptor (RXR), 27, 30, 42, 154, Tumor necrosis factor (TNF), 61, 102, 105,
156, 157, 159, 196, 197, 206, 207, 212, 107, 130–131, 225, 226
224, 232, 253, 254, 258, 268, 289
Retinoid X receptor alpha (RXRa), 154
Ribosomal s6 kinase (MAPK-activated protein U
kinase-1) (p90RSK ), 156, 157, 159 Ultraviolet (UV), 32, 36, 37, 41, 83, 89, 120,
121, 128, 156, 157, 193–196, 201, 203,
207–209, 211, 212, 226–228, 285, 297,
S 298, 316–318, 322, 328, 332
Seasonality, 75, 92, 106, 120, 121, 123, 185, Ultraviolet B light (UV-B), 3, 36, 74–76, 79, 82,
193, 202, 227, 281, 307, 308, 315, 317, 91, 106, 120, 128, 176, 183–184, 193, 195,
318, 320, 322, 323 207–209, 222, 228, 296, 315–317, 319, 320
Serine/threonine-specific protein kinase B
(AKT), 104, 152, 158, 159, 199, 209, 225,
232, 259, 261, 262 V
Silencing mediator of retinoid and thyroid Vascular smooth muscle cells (VSMCs), 103,
hormone receptors/Nuclear receptor 106–107
co-repressor 2 (NCOR2/SMRT), 27, 28, Vasculature, 100, 103, 107
31, 40 Vitamin D, 1–18, 73–92, 99–107, 115–132,
Simian virus 40 (SV40), 280 143–163, 175–187, 191–212, 221–241,
Skin cancer, 37, 74, 80, 88, 90, 176, 183, 187, 251–269, 279–290, 295–309, 315–323,
191–212, 295–296, 316 327–335
Solar UV radiation, 120, 195, 201 Vitamin D , 3, 15–16, 26, 32, 41, 107, 120,
3
Specificity protein 1(Sp-1), 149 122, 123, 128, 176–178, 180–186,
Squamous cell carcinoma (SCC), 17, 88, 103, 195–201, 257, 280, 283, 296–300, 304,
104, 152–154, 195, 201, 202, 206, 209, 316, 322, 323, 328–329, 331
228, 232 Vitamin D analogues, 7, 16, 17, 104, 105, 150,
SRA stem loop-interacting RNA-binding 177, 180, 181, 209, 211, 212, 231, 256,
protein (SLIRP), 28 261–268, 283–285, 287–289
Steroid receptor co-activator (SRC), 29, 30, Vitamin D assay, 14, 103, 119, 120, 155, 161,
154, 197, 198, 206, 233 177, 281, 297–302, 328–335
Vitamin D receptor (VDR), 2, 26, 62, 103,
3
147, 178, 193, 222, 253, 280, 296, 316, 334
T Vitamin D response element (VDRE), 30, 41,
3
T-cell transcription factor 4, 149 60, 148, 154, 156, 157, 159, 196–198, 206,
Thyroid hormone receptor interactor 2 224, 225, 260–262, 268
(TRIP2/DRIP205), 30
Thyroid hormone receptor interactor 15
(TRIP15/COPS2/Alien), 28 W
Transforming growth factor beta (TGFb), 101, Wild type (WT), 37, 56, 100, 104, 178, 179,
283, 287 183, 205, 207, 255, 267, 285, 287
TRIP15/COPS2/Alien. See Thyroid hormone Wingless-related MMTV integration site
receptor interactor 15 (Wnt), 6, 33, 34, 39, 147–149