Page 57 - Vitamin D and Cancer
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44 J. Thorne and M.J. Campbell
12. Nakabayashi M et al (2008) Crystal structures of rat vitamin D receptor bound to adamantyl
vitamin D analogs: structural basis for vitamin D receptor antagonism and partial agonism.
J Med Chem 51:5320–5329
13. Carlberg C, Molnar F (2006) Detailed molecular understanding of agonistic and antagonistic
vitamin D receptor ligands. Curr Top Med Chem 6:1243–1253
14. Saramaki A et al (2009) Cyclical chromatin looping and transcription factor association on
the regulatory regions of the p21 (CDKN1A) gene in response to 1alpha, 25-dihydroxyvita-
min D3. J Biol Chem 284(12):8073–82
15. Kim JY, Son YL, Lee YC (2009) Involvement of SMRT corepressor in transcriptional
repression by the vitamin D receptor. Mol Endocrinol 23:251–264
16. Li J et al (2000) Both corepressor proteins SMRT and N-CoR exist in large protein com-
plexes containing HDAC3. EMBO J 19:4342–4350
17. Malinen M et al (2007) Distinct HDACs regulate the transcriptional response of human
cyclin-dependent kinase inhibitor genes to trichostatin A and 1{alpha}, 25-dihydroxyvita-
min D3. Nucleic Acids Res 36(1):121–32
18. Yoon HG et al (2003) Purification and functional characterization of the human N-CoR
complex: the roles of HDAC3, TBL1 and TBLR1. EMBO J 22:1336–1346
19. Alenghat T, Yu J, Lazar MA (2006) The N-CoR complex enables chromatin remodeler
SNF2H to enhance repression by thyroid hormone receptor. EMBO J 25(17):3966–74
20. Yu C et al (2005) The nuclear receptor corepressors NCoR and SMRT decrease PPARgamma
transcriptional activity and repress 3T3-L1 adipogenesis. J Biol Chem 280(14):13600–5
21. Oda Y et al (2003) Two distinct coactivators, DRIP/mediator and SRC/p160, are differen-
tially involved in vitamin D receptor transactivation during keratinocyte differentiation. Mol
Endocrinol 17:2329–2339
22. Rachez C et al (2000) The DRIP complex and SRC-1/p160 coactivators share similar nuclear
receptor binding determinants but constitute functionally distinct complexes. Mol Cell Biol
20:2718–2726
23. Saramaki A, Banwell CM, Campbell MJ, Carlberg C (2006) Regulation of the human
p21(waf1/cip1) gene promoter via multiple binding sites for p53 and the vitamin D3 recep-
tor. Nucleic Acids Res 34:543–554
24. Vaisanen S, Dunlop TW, Sinkkonen L, Frank C, Carlberg C (2005) Spatio-temporal
Activation of Chromatin on the Human CYP24 Gene Promoter in the Presence of 1alpha,
25-Dihydroxyvitamin D(3). J Mol Biol 350(1):65–77
25. Zella LA, Kim S, Shevde NK, Pike JW (2006) Enhancers located within two introns of the
vitamin D receptor gene mediate transscriptional autoregulation by 1, 25-dihydroxyvitamin
D3. Mol Endocrinol 103(3–5):435–9
26. Kim S, Shevde NK, Pike JW (2005) 1, 25-Dihydroxyvitamin D3 stimulates cyclic vitamin
D receptor/retinoid X receptor DNA-binding, co-activator recruitment, and histone acetyla-
tion in intact osteoblasts. J Bone Miner Res 20:305–317
27. Seo YK et al (2007) Xenobiotic- and vitamin D-responsive induction of the steroid/bile acid-
sulfotransferase Sult2A1 in young and old mice: the role of a gene enhancer in the liver
chromatin. Gene 386:218–223
28. Meyer MB, Watanuki M, Kim S, Shevde NK, Pike JW (2006) The human TRPV6 distal
promoter contains multiple vitamin D receptor binding sites that mediate activation by 1,
25-dihydroxyvitamin D3 in intestinal cells. Mol Endocrinol 20(6):1447–61
29. Reid G et al (2003) Cyclic, proteasome-mediated turnover of unliganded and liganded ERalpha
on responsive promoters is an integral feature of estrogen signaling. Mol Cell 11:695–707
30. Metivier R et al (2003) Estrogen receptor-alpha directs ordered, cyclical, and combinatorial
recruitment of cofactors on a natural target promoter. Cell 115:751–763
31. Yang X et al (2006) Nuclear receptor expression links the circadian clock to metabolism.
Cell 126:801–810
32. Carroll JS et al (2006) Genome-wide analysis of estrogen receptor binding sites. Nat Genet
38:1289–1297